Search Menu

Canine herpes virus, more commonly known as fading puppy syndrome, can be a devastating disease if it hits your kennel.

Dogs typically become exposed by nose to nose contact with an infected dog or through the air in crowded areas. Dogs at highest risk for the virus are young females who’ve never been exposed and their newborn puppies. Puppies can be infected in utero, through exposure to infected secretions of the dam, or through postnatal exposure to infected older members of the household dogs and/or kennel.

In dogs older than 12 weeks, mild respiratory disease is the most common clinical sign. But infections occurring in pregnant dams, who have not been exposed, can cause severe problems for the puppies, including fetal death and abortion.

Infection in puppies less than 2 to 3 weeks of age is usually fatal. Signs include trouble breathing, discharge from the nose, not nursing, persistent crying and hemorrhage (red spots) on the gums. The time from when the puppy is initially infected until it shows symptoms is four to six days, and the onset is sudden. After clinical signs arise, death usually occurs in 24 to 36 hours. Some puppies with mild signs may survive but can later develop serious neurological issues, such as trouble walking and blindness. Unfortunately, treatment in severely infected puppies is not rewarding, as there is almost a 100% mortality rate.

The best medicine for this virus is prevention. Since the virus is spread primarily by air and direct contact with nasal secretions, sanitation is an important part of prevention. Good hand hygiene should be used by anyone handling the mother and her puppies. Crowded conditions should be avoided. Keep the dam’s and puppies’ area clean and disinfected. Common disinfectants are effective in destroying the herpes virus.

For the last three weeks of gestation, pregnant females should be kept separate from other dogs in the family/kennel. Mother and puppies also should be kept separate for the first three weeks after birth. This is to prevent exposure to dogs who may carry the virus but do not show signs. Rearing the litter in temperatures greater than 95 degrees may also reduce losses in exposed litters.

A vaccine has been developed in Europe, but the benefits are still not known, and the vaccine is not licensed for the United States.

Puppies nursing from bitches that have previously been exposed to the virus are resistant to infection as they receive antibodies from colostrum. After a bitch has lost a litter due to herpes virus, she can be expected to have normal subsequent litters.

With the proper knowledge and prevention, this deadly virus can be avoided in your breeding program.

This article is intended solely as general guidance, and does not constitute health or other professional advice. Individual situations and applicable laws vary by jurisdiction, and you are encouraged to obtain appropriate advice from qualified professionals in the applicable jurisdictions. We make no representations or warranties concerning any course of action taken by any person following or otherwise using the information offered or provided in this article, including any such information associated with and provided in connection with third-party products, and we will not be liable for any direct, indirect, consequential, special, exemplary or other damages that may result, including but not limited to economic loss, injury, illness or death.
Get Your Free AKC eBook

Breeder Education Courses

Training isn't just for pets - here's your chance to learn too. Visit the AKC Breeder Education Platform designed to support your continuing education needs. Course topics include introduction to breeding, genetics, anatomy, whelping and nutrition.
*Turn off pop-up blocker to download
*Turn off pop-up blocker to download