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Just like us, dogs are susceptible to minor cuts, scrapes, and scratches. And, just like us, dogs can benefit from many of the same medications. But is Neosporin® safe for dogs?

Key Points

“Typically, small amounts of Neosporin are not harmful,” says Dr. Danel Grimmett, DVM, with Sunset Veterinary Clinic in Oklahoma.

In general, as long as your dog isn’t allergic to Neosporin or accidentally eats it, the ointment could go a long way in preventing infection and promoting healing. If you ever have questions regarding your dog’s health, including whether an injury requires emergency care, consult their veterinary team.

What to Know About Using Neosporin on Your Dog

To maximize Neosporin’s potential benefits, there are a few things to keep in mind. First, while Neosporin isn’t FDA-approved for use in animals, it can be used off-label for dogs. Second, the ointment relies on three antibiotics to kill and prevent the growth of bacteria: bacitracin, neomycin, and polymyxin B. However, one of these medications poses a slight risk to dogs.

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“Bacitracin has been deemed safe for use on animals, as has polymyxin B. However, neomycin has been linked to loss of hearing,” explains Dr. Rachel Barrack, a licensed veterinarian certified in both veterinary acupuncture and Chinese herbology with Animal Acupuncture in New York City. “This was primarily shown with intravenous use, but it is recommended that you do not administer neomycin topically to your dog without first consulting your vet.”

Because Neosporin is a topical ointment applied directly to the skin, there’s always a chance that your dog could have an allergic reaction. To check, administer a small patch test. Do this by picking a small area of skin and applying a tiny dab of Neosporin. Then, monitor the area for any to see if your dog develops a mild rash, redness, or hives. The results will inform whether Neosporin is a good choice for your dog.

How to Use Neosporin on Your Dog

Neosporin isn’t suited for uncontrollably bleeding wounds or puncture wounds that require stitches. It’s recommended for skin-level use only; if your dog has a deep gash (like from a dog bite), you should consult a veterinarian immediately. They may recommend stitches, drains, or bandages, depending on the severity.

After you’ve determined that your dog isn’t allergic to Neosporin and they don’t require emergency veterinary care, you can apply the ointment by:

  • Flushing the wound with soap and water. This will also give you more insight into the severity of your dog’s injury and whether you should they need to visit a professional.
  • Rinsing the area thoroughly, ensuring to wash away any residual soap or water. Pat the wet area dry to ensure the Neosporin isn’t diluted or washed away entirely.
  • Applying the ointment. Squeeze a small dab of Neosporin onto a Q-tip and apply it to the affected area. Spread a thin layer of the lotion or gel over the surface area of the wound surface one to three times a day until it heals.

From there, monitor your dog’s healing process to gauge the treatment’s effectiveness. You may attempt to bandage the wound, but note that the pros may outweigh the cons this could have more cons than pros. 

“A bandage can act as a tourniquet, reducing adequate blood flow to extremities, if not managed well,” says Dr. Grimmett. “Great care must be taken to prevent any constriction.”

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Precautions When Using Neosporin on Dogs

If your dog’s wound is in a spot they can easily reach, they might try licking the Neosporin off, which not only defeats the purpose but might also make them sick.

“The main concern regarding ingestion of Neosporin is the potential impact [on] the GI flora (normal gut bacteria), resulting in GI upset, such as vomiting and diarrhea,” says Dr. Grimmett. “A second potential cause of GI upset would be the lubricant base, which could also give them diarrhea, etc.”

Ensuring your dog gets the maximum benefit from Neosporin involves ensuring the wound stays untouched. You may consider getting an Elizabethan collar to limit your dog’s range of movement motion while the wound heals. Some of these collars are plastic cones, while others are inflatable donuts you can affix around your dog’s neck.

There are other pet garments, such as surgical recovery suits, that can also prevent licking and keep the ointment’s protective barrier intact.

Alternatives to Neosporin for Dogs

If your dog suffered a superficial wound that you feel confident treating at home, you have many alternatives to Neosporin. Some antibiotic ointments for dogs, like Animax and Mupirocin, are formulated specifically for dogs and only available with a prescription. These offer the same benefits as Neosporin.

There are other remedies that could also encourage healing and prevent infection, such as:

  • Over-the-counter wound care spray. You don’t need a prescription for many pet-friendly antimicrobial wound care sprays. Some formulations rely on plant-based ingredients to create a cellulose film over an open wound, protecting it from dust, dirt, and other debris.
  • Certain types of honey. Honey naturally contains antibacterial and anti-inflammatory properties proven to help repair damaged tissue. Studies show that medical-grade honey is the most effective. Manuka honey, only made by bees that pollinate Australia’s manuka tree, is another popular choice.

Talk to your veterinarian to learn more about possible alternatives to Neosporin and other measures that could benefit their health.

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Protect Your Dog from Cuts, Scratches, and Scrapes

Minor scrapes and scratches are just part of an active dog’s life. Having a first-aid kit prepared in the event your dog gets hurt can go a long way toward helping you quickly intervene to prioritize their health, safety, and comfort. In addition to Neosporin (or another pet-friendly topical ointment), you may also keep bandages, cotton balls, and gauze on hand when you and your dog are out and about.

It’s important to first talk with your veterinarian before administering any new medications. “Your veterinarian is better equipped to treat your dog’s potential infections than you are at home,” says Dr. Barrack.

This article is intended solely as general guidance, and does not constitute health or other professional advice. Individual situations and applicable laws vary by jurisdiction, and you are encouraged to obtain appropriate advice from qualified professionals in the applicable jurisdictions. We make no representations or warranties concerning any course of action taken by any person following or otherwise using the information offered or provided in this article, including any such information associated with and provided in connection with third-party products, and we will not be liable for any direct, indirect, consequential, special, exemplary or other damages that may result, including but not limited to economic loss, injury, illness or death.

Related article: When Should I Call the Vet?
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