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AKC DNA + Health

Breed-Specific DNA Testing Recommendations

Test for what is recommended for your breed, not everything available.

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The AKC DNA Program recommends that breeders perform DNA tests that are relevant to their breed. Although the AKC DNA + Health Kit includes over 328 markers for health and traits, not all genetic variants have been validated in every breed. Some tests may have significance in some breeds, but a positive results may not cause disease in another breed. Additionally, some genetic tests are not included in the AKC DNA + Health Kit. Breeders may also choose to make breeding decisions based on genetic tests that are not included in Parent Club recommendations, but may still be relevant to their breed or line. For a list of all included tests, click here.

The following DNA tests are recommended for each breed based on Parent Club recommendations. Most DNA tests are included in the AKC DNA + Health Kit. Tests that are not included are marked as “Not included in AKC DNA + Health.” Some DNA tests are optional and not required for the AKC Breeder of Merit or AKC Bred with H.E.A.R.T. certifications. A complete list of breed health testing requirements can be found here. For more information about how these recommendations are made, click here.

  • Alaskan Klee Kai
    • Coagulation Factor VII Deficiency
  • Alaskan Malamute
    • Alaskan Malamute Polyneuropathy (AMPN)
    • Optional:
      • Cone Degeneration (CD)
      • Primary Ciliary Dyskinesia (PCD)
  • American Bulldog
    • Hyperuricosuria (HUU)
  • American Eskimo Dog
    • Progressive Retinal Atrophy (PRA-prcd, PRCD)
  • American Staffordshire Terrier
    • Neuronal Ceroid Lipofuscinosis 4A (NCL, NCL4A)
  • Appenzeller Sennenhund
    • Optional:
      • Degenerative Myelopathy (Common Variant) (DM)
  • Australian Cattle Dog
    • Primary Lens Luxation (PLL)
    • Progressive Retinal Atrophy (PRA-prcd, PRCD)
  • Australian Shepherd
    • Optional:
      • Hereditary Cataracts (Australian Shepherd) (HC, HSF4, JC)
      • Multidrug Resistance 1 (MDR1)
      • Collie Eye Anomaly (CEA, CH)
  • American Stumpy Tail Cattle Dog
    • Hyperuricosuria (HUU)
  • Barbet
    • D-Locus
  • Basenji
    • Progressive Retinal Atrophy (Basenji) (PRA)
    • Fanconi’s Syndrome, Paradoxic glucosuria
  • Basset Hound
    • Mucopolysaccharoidosis (MPSI) – Not included in AKC DNA + Health
    • Thrombopathia (Basset Hound)
    • Primary Open Angle Glaucoma (Basset Hound) (POAG)
    • Lafora Disease – Not included in AKC DNA + Health
  • Beagle
    • Musladin-Leuke Syndrome (MLS)
    • Optional:
      • Coagulation Factor VII Deficiency
      • Neonatal Cerebellar Cortical Degeneration (NCCD)
      • Lafora Disease – Not included in AKC DNA + Health
  • Bedlington Terrier
      • Copper Toxicosis
        • Please note: AKC DNA + Health screens for one genetic variant associated with copper toxicosis, but other variants also exist that are associated with this disease.
  • Bergamasco
    • Degenerative Myelopathy (Common Variant) (DM)
  • Bernese Mountain Dog
    • Degenerative Myelopathy (Common Variant) (DM)
    • Degenerative Myelopathy (Bernese Mountain Dog Variant) (DM)
    • AKC DNA Profile
    • Optional:
      • Von Willebrand Disease I (VWDI)
      • Histiocytic sarcoma risk test – Not included in AKC DNA + Health
  • Biewer Terrier
    • Primary Lens Luxation (PLL)
    • Progressive Retinal Atrophy (PRA-prcd, PRCD)
    • Optional:
      • Degenerative Myelopathy (Common Variant) (DM)
      • Hyperuricosuria (HUU)
  • Black Russian Terrier
    • Juvenile Laryngeal Paralysis & Polyneuropathy (JLPP, POANV)
  • Bloodhound
    • Optional:
      • Degenerative Myelopathy (Common Variant) (DM)
  • Border Terrier
    • Spongiform Leukoencephalomyelopathy (SLEM) – Not included in AKC DNA + Health
  • Borzoi
    • Degenerative Myelopathy (Common Variant) (DM)
  • Boston Terrier
    • Optional:
      • Hereditary Cataracts (HC, JC)
  • Boxer
    • Optional:
      • Arrythmogenic Right Ventricular Cardiomyopathy (ARVC) DNA Test – Not included in AKC DNA + Health
      • Degenerative Myelopathy (Common Variant) (DM)
  • Boykin Spaniel
    • Collie Eye Anomaly (CEA, CH)
    • Exercise Induced Collapse (EIC)
  • Briard
    • Congenital Stationary Night Blindness (CSNB, LCA)
  • Cairn Terrier
    • Globoid Cell Leukodystrophy (Terrier) (GLD)
  • Cardigan Welsh Corgi
    • Degenerative Myelopathy (Common Variant) (DM)
    • Progressive Retinal Atrophy, Rod-Cone Dysplasia 3 (PRA-rcd3)
  • Cavalier King Charles Spaniel
    • Optional:
      • Degenerative Myelopathy (Common Variant) (DM)
      • Dry Eye Curly Coat Syndrome (CKSID)
      • Episodic Falling Syndrome (EDFS)
  • Cesky Terrier
    • Optional:
      • Primary Lens Luxation (PLL)
  • Chesapeake Bay Retriever
    • Degenerative Myelopathy (Common Variant) (DM)
    • Progressive Retinal Atrophy (PRA-prcd, PRCD)
  • Chinese Crested
    • Primary Lens Luxation (PLL)
    • Progressive Retinal Atrophy, PRCD (PRA-prcd, PRCD)
    • Progressive Retinal Atrophy, Rod-Cone Dysplasia 3 (PRA-rcd3)
  • Chinook
    • Chondrodysplasia (Karelian Bear Dog & Norwegian Elkhound)
    • Multidrug Resistance (MDR1)
      • Optional:
        • Degenerative Myelopathy (Common Variant) (DM)
        • Intervertebral Disc Disease & Chondrodystrophy (IVDD)
  • Clumber Spaniel
    • Pyruvate Dehydrogenase Deficiency (PDP1)
  • Collie
    • Multidrug Resistance 1 (MDR1)
    • Collie Eye Anomaly (CEA, CH)
  • Coton de Tulear
    • Bander’s Neonatal Cerebellar Ataxia (BNA) – Not included in AKC DNA + Health
    • Degenerative Myelopathy (Common Variant) (DM)
    • Hyperuricosuria (HUU)
    • Multifocal Retinopathy 2 (CMR2)
    • Primary Hyperoxyluria (PH1)
    • Von Willebrand Disease I (VMD1)
  • Curly-Coated Retriever
    • Glycogen Storage Disease IIIa (GSD IIIa)
    • Exercise Induced Collapse (EIC)
    • Progressive Retinal Atrophy, Cone-Rod Dystrophy 4 (crd4/cord1) (PRA-crd4/cord1)
  • Czechoslovakian Vlack
    • Degenerative Myelopathy (Common Variant) (DM)
  • Doberman Pinscher
    • Von Willebrand Disease I (VWDI)
  • English Cocker Spaniel
    • Progressive Retinal Atrophy, PRCD (PRA-prcd, PRCD)
    • Optional:
      • Familial Nephropathy (Cocker Spaniel) (FN, HN)
      • Adult-Onset Neuropathy (AON) – Not included in AKC DNA + Health
  • English Springer Spaniel
    • Glycogen Storage Disease VII, PFK Deficiency (GSD VII, PFK deficiency)
    • Progressive Retinal Atrophy, Cone-Rod Dystrophy 4 (crd4/cord1) (PRA-crd4/cord1),
  • Entlebucher Mountain Dog
    • AKC DNA Profile
    • Progressive Retinal Atrophy, PRCD (PRA-prcd, PRCD)
  • Finnish Lapphund
    • Degenerative Myelopathy (Common Variant) (DM)
    • Pompe Disease (GSDII)
    • Progressive Retinal Atrophy, PRCD (PRA-prcd, PRCD)
  • German Wirehaired Pointer
    • Optional:
      • Von Willebrand Disease I (VWDI)
  • German Pinscher
    • Von Willebrand Disease I (VWDI)
  • German Shorthaired Pointer
    • Cone Degeneration (German Shorthaired Pointer) (CD)
    • Optional:
      • Von Willebrand Disease II (VWDII)
  • Glen of Imaal Terrier
    • Progressive Retinal Atrophy, Cone-Rod Dystrophy 3 (PRA-crd3)
  • Golden Retreiver
    • Neuronal Ceroid Lipofuscinosis 5 (Golden Retriever) (NCL, NCL5)
  • Gordon Setter
    • Progressive Retinal Atrophy, Rod-Cone Dysplasia 4 (PRA-rcd4)
  • Great Pyranees
    • Glanzmann’s Thrombasthenia (Great Pyrenees) (GT)
    • Multifocal Retinopathy 1 (CMR1)
    • Optional:
      • Neuronal Degeneration (NDG) and Dwarfism – Not included in AKC DNA + Health
  • Greyhound
    • Greyhound Polyneuropathy
  • Hamiltonstovare
    • Optional:
      • Degenerative Myelopathy (Common Variant) (DM)
  • Irish Red and White Setter
    • Leukocyte Adhesion Deficiency, Type I (CLAD, LAD-A)
    • Optional:
      • Progressive Retinal Atrophy (Irish Setter) (PRA-rcd1)
      • Von Willebrand Disease I (VWDI)
  • Irish Setter
    • Progressive Retinal Atrophy (Irish Setter) (PRA-rcd1)
    •  Optional:
      • Leukocyte Adhesion Deficiency, Type I (CLAD, LAD-A)
      • Progressive Retinal Atrophy, Rod-Cone Dysplasia 4 (PRA-rcd4)
  • Irish Terrier
    • Optional:
      • Hereditary Footpad Hyperkeratosis (Irish Terrier & Kromfohrländer)
  • Italian Greyhound
    • Optional:
      • Amelogenesis Imperfecta (AI, ARAO)
      • Progressive Retinal Atrophy, PRA1 (Papillon Type) (PRA, PRA1)
      • Acute Narrow Angle Glaucoma – Not Included in AKC DNA + Health
  • Japanese Chin
    • GM2 Gangliosidosis (Japanese Chin)
  • Keeshond
    • Primary Hyperparathyroidism – Not Included in AKC DNA + Health
  • Komondor
    • Optional
      • Degenerative Myelopathy (Common Variant) (DM)
  • Kromfohrlander
  • Kuvasz
    • Optional:
      • Progressive Retinal Atrophy, PRCD (PRA-prcd, PRCD)
  • Labrador Retriever
    • Exercise Induced Collapse (EIC)
    • D-Locus (Dilute)
    • Progressive Retinal Atrophy, PRCD (PRA-prcd, PRCD)
    • Centronuclear Myopathy (CNM)
  • Lagotto Romagnolo
    • Benign Familial Juvenile Epilepsy (BFJE)
    • Lagotto Storage Disorder (LSD)
    • Optional:
      • IC Locus (Improper Coat)
  • Lancashire Heeler
    • Collie Eye Anomaly (CEA, CH)
    • Primary Lens Luxation (PLL)
  • Leonberger
    • Leonberger Polyneuropathy 1 (LPN1), aka Polyneuropathy (Leonberger & Saint Bernard) (PN))
    • Polyneuropathy (Leonberger Type 2) (PN, LPN2)
    • Laryngeal Paralysis and Polyneuropathy (Leonberger Type 3)
    • Leukocencephalomyelopathy (LEMP)
  • Manchester Terrier – Standard
    • Von Willebrand Disease I (VWDI)
    • Optional:
      • Juvenile DCM in Manchester Terriers – Not Included in AKC DNA + Health
      • Xanthinuria Type II – Not Included in AKC DNA + Health
  • Manchester Terrier – Toy
    • Von Willebrand Disease I (VWDI)
    • Juvenile DCM in Manchester Terriers – Not Included in AKC DNA + Health
    • Xanthinuria Type II – Not Included in AKC DNA + Health
  • Miniature American Shepherd
    • Multidrug Resistance 1 (MDR1)
    • Progressive Retinal Atrophy, PRCD (PRA-prcd, PRCD)
  • Miniature Bull Terrier
    • Primary Lens Luxation (PLL)
    • Lethal Acrodermatitis (LAD)
    • Laryngeal Paralysis (Miniature Bull Terrier Type) – Not Included in AKC DNA + Health
  • Miniature Pinshcer
    • Mucopolysaccharoidosis IV (MPSIV) – Not included in AKC DNA + Health
  • Mountain Cur
    • Collie Eye Anomaly (CEA, CH)
    • Degenerative Myelopathy (Common Variant) (DM)
  • Mudi
    • Optional:
      • Multidrug Resistance 1 (MDR1)
  • Nederlandse Kooikerhondje
    • Von Willebrand Disease III (Kooikerhondje) (VWDIII)
    • Hereditary Necrotizing Myelopathy (ENM) – Not Included in AKC DNA + Health
  • Newfoundland
    • Cystinuria (Newfoundland)
  • Norfolk Terrier
    • Epidermolytic Hyperkeratosis
  • Nova Scotia Duck Tolling Retreiver
    • Progressive Retinal Atrophy, PRCD (PRA-prcd, PRCD)
    • Cleft Palate & Syndactyly (Nova Scotia Duck Tolling Retriever) (CP1, CLPS)
    • Juvenile Addison’s Disease (JADD) – Not Included in AKC DNA + Health
  • Old English Sheepdog
    • Exercise Induced Collapse (EIC)
    • Optional:
      • Multidrug Resistance 1 (MDR1)
      • Cerebellar Degeneration (HA, CA)
      • Primary Ciliary Dyskinesia (PCD)
  • Otterhound
    • Glanzmann’s Thrombasthenia (Otterhound) (GT)
  • Papillon
    • Optional:
      • Progressive Retinal Atrophy, PRA1 (Papillon Type) (PRA, PRA1)
      • Neuroaxonal Dystrophy (Papillon Type) (NAD)
  • Parson Russell Terrier
    • Optional:
      • Primary Lens Luxation (PLL)
      • Late Onset Ataxia (LOA, SCA) – CAPN1 gene
      • Spinocerebellar Ataxia (SCA, KCNJ10 gene), aka Spinocerebellar Ataxia with Myokymia seizures
  • Petit Basset Griffon Vendeen
    • Primary Open Angle Glaucoma (Basset Fauve de Bretagne Type) (POAG)
  • Poodle
    • Progressive Retinal Atrophy, PRCD (PRA-prcd, PRCD)
    • Progressive Retinal Atrophy, Rod-Cone Dysplasia 4 (PRA-rcd4)
    • Von Willebrand Disease I (VWDI)
  • Portuguese Water Dog
    • GM1 Gangliosidosis (Portuguese Water Dog),
    • Progressive Retinal Atrophy, PRCD (PRA-prcd, PRCD),
    • Progressive Retinal Atrophy, Early-Onset (Portuguese Water Dog Type),
    • Juvenile Dilated Cardiomyopathy (JDCM, Portuguese Water Dog Type) – Not Included in AKC DNA + Health
    • Microphthalmia Syndrome (MO, Portuguese Water Dog Type)- Not Included in AKC DNA + Health
    • Optional:
      • IC Locus (Improper Coat)
  • Pug
    • Pug Dog Encephalitis (PDE) aka Necrotizing Meningioencephalitis (NME) – Not Included in AKC DNA + Health
    • Pyruvate Kinase Deficiency (Pug Type) (PKD)
  • Puli
    • Degenerative Myelopathy (Common Variant) (DM)
  • Pumi
    • Degenerative Myelopathy (Common Variant) (DM)
    • Primary Lens Luxation (PLL)
  • Rat Terrier
    • Primary Lens Luxation (PLL)
  • Rhodesian Ridgeback
    • Optional:
      • Degenerative Myelopathy – Common Variant (DM)
      • Juvenile Myoclonic Epilepsy (JME)
      • Early Onset Adult Deafness (EOAD)
  • Rottweiler
    • Juvenile Laryngeal Paralysis and Polyneuropathy (JLPP)
  • Russell Terrier
    • Primary Lens Luxation (PLL)
  • Samoyed
    • Progressive Retinal Atrophy, X-Linked 1 (XLPRA1)
    • Retinal Dysplasia/Oculoskeletal Dysplasia 1 (OSD1, DRD1, RD/OSD1)
  • Schipperke
    • Optional:
      • Mucopolysaccharidosis type IIIB (MPS)
  • Scottish Deerhound
    • Coagulation Factor VII Deficiency
    • Delayed Post-Operative Hemorrhage (DEPOH) – Not Included in AKC DNA + Health
  • Scottish Terrier
    • Von Willebrand Disease III (Scottish Terrier) (VWDIII)
  • Sealyham Terrier
    • Primary Lens Luxation (PLL)
  • Shetland Sheepdog
    • Optional:
      • Collie Eye Anamoly (CEA, CH)
      • Multiple Drug Sensitivity (MDR1)
      • Von Willebrand Disease III (Shetland Sheepdog) (VWDIII)
      • Dermatomyositis – Loci A, B, and C – Not Included in AKC DNA + Health
  • Sloughi
    • Progressive Retinal Atrophy (Sloughi Type) (PRA-rcd1a)
  • Soft Coated Wheaten Terrier
    • Protein Losing Nephropathy (PLN), 2 Variants
  • Spanish Water Dog
    • Neuroaxonal Dystrophy (Spanish Water Dog) (NAD)
  • Saint Bernard
    • Degenerative Myelopathy (Common Variant) (DM)
  • Staffordshire Bull Terrier
    • Hereditary Cataracts (HC, JC)
    • L-2-Hydroxyglutaric Aciduria (Staffordshire Bull Terrier) (L-2-HGA)
  • Standard Schnauzer
    • Dilated Cardiomyopathy (Schnauzer) (DCM)
  • Swedish Vallhund
    • Swedish Vallhund Retinopathy – Not Included in AKC DNA + Health
  • Teddy Roosevelt Terrier
    • Primary Lens Luxation (PLL)
  • Tibetan Spaniel
    • Optional:
      • Progressive Retinal Atrophy, PRA3 (Tibetan Terrier & Spaniel Type) (PRA3)
  • Tibetan Terrier
    • Primary Lens Luxation (PLL)
    • Progressive Retinal Atrophy, Rod-Cone Dysplasia 4 (PRA-rcd4)
    • Progressive Retinal Atrophy, PRA3 (Tibetan Terrier & Spaniel Type) (PRA3)
    • Neuronal Ceroid Lipofuscinosis (Tibetan Terrier) (NCL)
  • Toy Fox Terrier
    • Primary Lens Luxation (PLL)
  • Weimaraner
    • Hyperuricosuira (HUU)
    • Hypomyelination (HYM)
    • Spinal Dysraphisim (SD)
  • Welsh Terrier
    • Primary Lens Luxation (PLL)
  • Wetterhoun
  • Wirehaired Vizsla
    • Optional:
      • Hyperuricosuria (HUU)

The following breeds have no recommended or optional DNA health tests per their Parent Club Health Statement. However, a breeder may still choose to test their dogs for genetic variants that are relevant to their lines. Some breeders may also be interested in trait testing provided by AKC DNA + Health.

  • Affenpinscher
  • Afghan Hound
  • Airedale Terrier
  • Akita
  • American Hairless Terrier
  • American English Coonhound
  • American Foxhound
  • American Leopard Hound
  • American Water Spaniel
  • Anatolian Shepherd
  • Australian Kelpie
  • Australian Terrier
  • Azawakh
  • Barbado de Terceira
  • Basset Fauve de Bretagne
  • Bavarian Mountain Scent Hound
  • Bearded Collie
  • Beauceron
  • Belgian Laekenois
  • Belgian Malinois
  • Belgian Sheepdog
  • Belgian Tervuren
  • Berger Picard
  • Bichon Frise
  • Black and Tan Coonhound
  • Bluetick Coonhound
  • Boerboel
  • Bohemian Shepherd
  • Bolognese
  • Border Collie
  • Bouvier des Flandres
  • Bracco Italiano
  • Braque du Bourbonnais
  • Braque Francais Pyrenean
  • Brittany
  • Broholmer
  • Brussels Griffon
  • Bull Terrier
  • Bulldog
  • Bullmastiff
  • Canaan Dog
  • Cane Corso
  • Carolina Dog
  • Catahoula Leopard Dog
  • Caucasian Shepherd Dog
  • Central Asian Shepherd Dog
  • Chihuahua
  • Chinese Shar-Pei
  • Chow Chow
  • Cirneco dell’Etna
  • Cocker Spaniel
  • Croatian Sheepdog
  • Dachshund
  • Dalmatian
  • Dandie Dinmont Terrier
  • Danish-Swedish Farmdog
  • Deutscher Wachtelhund
  • Dogo Argentino
  • Dogue de Bordeaux
  • Drentsche Patrijshond
  • Drever
  • Dutch Shepherd
  • English Setter
  • English Foxhound
  • English Toy Spaniel
  • Eurasier
  • Field Spaniel
  • Finnish Spitz
  • Flat-Coated Retriever
  • French Bulldog
  • French Spaniel
  • German Longhaired Pointer
  • German Shepherd Dog
  • Grand Basset Griffon Vendeen
  • Great Dane
  • Greater Swiss Mountain Dog
  • Hanoverian Scenthound
  • Harrier
  • Havanese
  • Hokkaido
  • Hovawart
  • Ibizan Hound
  • Icelandic Sheepdog
  • Irish Water Spaniel
  • Irish Wolfhound
  • Jagdterrier
  • Japanese Akitainu
  • Japanese Spitz
  • Japanese Terrier
  • Jindo
  • Kai Ken
  • Karelian Bear Dog
  • Kerry Blue Terrier
  • Kishu Ken
  • Lakeland Terrier
  • Lapponian Herder
  • Lhasa Apso
  • Lowchen
  • Maltese
  • Mastiff
  • Miniature Schnauzer
  • Neapolitan Mastiff
  • Norrbottenspets
  • Norwegian Buhund
  • Norwegian Elkhound
  • Norwegian Lundehund
  • Norwich Terrier
  • Pekingese
  • Pembroke Welsh Corgi
  • Perro de Presa Canario
  • Peruvian Inca Orchid
  • Pharoah Hound
  • Plott Hound
  • Pointer
  • Polish Lowland Sheepdog
  • Pomeranian
  • Porcelaine
  • Portuguese Podengo
  • Portuguese Podengo Pequeno
  • Portuguese Pointer
  • Portuguese Sheepdog
  • Pudelpointer
  • Pyrenean Mastiff
  • Pyrenean Shepherd
  • Rafeiro do Alentejo
  • Redbone Coonhound
  • Romanian Carpathian Shepherd
  • Romanian Miortic Shepherd Dog
  • Russian Toy
  • Russian Tsvetnaya Bolonka
  • Saluki
  • Schapendoes
  • Segugio Italiano
  • Shiba Inu
  • Shikoku
  • Shih Tzu
  • Siberian Husky
  • Silky Terrier
  • Skye Terrier
  • Slovakian Wirehaired Pointer
  • Slovensky Cuvac
  • Slovensky Kopov
  • Small Munsterlander
  • Smooth Fox Terrier
  • Spanish Mastiff
  • Spinone Italiano
  • Stabyhoun
  • Sussex Spaniel
  • Swedish Lapphund
  • Thai Ridgeback
  • Tibetan Mastiff
  • Tornjak
  • Tosa
  • Transylvanian Hound
  • Treeing Tennessee Brindle
  • Treeing Walker Coonhound
  • Vizsla
  • Volpino Italiano
  • Welsh Springer Spaniel
  • West Highland White Terrier
  • Whippet
  • Wire Fox Terrier
  • Wirehaired Pointing Griffon
  • Working Kelpie
  • Xoloitcuintli (Standard)
  • Xoloitcuintli (Toy/Mini)
  • Yakutian Laika
  • Yorkshire Terrier