|The CHIC DNA Repository
Jointly sponsored by the Orthopedic Foundation for Animals and the AKC Canine Health Foundation, the CHIC DNA Repository collects and stores DNA samples along with corresponding pedigree and phenotypic health information to facilitate canine health research. The bank’s specific objectives are
The program began as a pilot project in 2005 with the Golden Retriever Club of America and opened up to all breeds in spring 2006. To date, over 3,000 samples have been collected, representing more than 60 different breeds.
- to facilitate more rapid research progress by expediting the sample collection process,
- to provide researchers with optimized family groups,
- to allow breeders to take advantage of future DNA based tests as they become available, and
- to foster a team environment between breeders and researchers, improving the likelihood of scientific discovery.
Samples can be collected via whole blood or buccal swabs. The CHIC DNA Repository has partnered with the Veterinary Genetics Lab at the University of California–Davis, which stores swab-based samples, and the Small Animal Molecular Genetics Lab at the University of Missouri, which processes and stores blood-based DNA samples.
Though it may be many years before the bank is sufficiently populated to routinely be of use to the research community, the bank recently approved its first sample allocation to Drs. Cheryl London (Ohio State) and Kirsten Linblad-Toh (Broad Institute/MIT) for a mast-cell tumor study in Golden Retrievers. This distribution is significant as a “proof of concept” test case in which two prominent researchers queried the database for relevant samples, found samples that would be of use to their project, applied for sample distribution, and subsequently received DNA from the bank to further their research efforts.
Samples can be submitted independently by owners, or parent clubs can schedule collection clinics in conjunction with their national specialty shows. For more information about the CHIC DNA Repository, or to download the application forms to submit a sample, visit the CHIC web site. —Eddie Dziuk, OFA chief operating officer
Upcoming CHIC DNA Clinics
American Bloodhound Club, Oct. 3, Denton, Texas
Montgomery County KC All-terrier Clinic, Oct. 7, Blue Bell, Pa.
English Setter Association of America, Oct. 11, Cincinnati